Update (6:30 p.m.)
The scene of the accident was cleared and U.S. 52 south of Brookville reopened around 5:50 p.m.
Dispatchers say six people were involved in the two-car crash.
Three medical helicopters were dispatched to the area.
First Report (4:45 p.m.)
FRANKLIN COUNTY, Ind. — Authorities are on the scene of a serious crash on U.S. 52 south of Brookville that occured around 4:00 p.m. Friday.
The accident has closed U.S. 52 from Brookville to State Road 1 South near Cedar Grove.
Dispatchers say three University of Cincinnati Air Care units have flown to the scene.
They were unable to confirm the number vehicles or people involved.
WRBI is covering this developing story and will report new details when they are made available.